Endocrine Abstracts

Introduction: Gastroparesis is defined by a delayed gastric emptying without mechanical obstruction. It can be a debilitating complication of diabetes that is poorly understood and has limited therapeutic options.Case reports: 1st case - We report the case of a 34-year-old woman with type 1 diabetes mellitus (T1DM) with diabetic nephropathy and gastroparesis, and a reasonable glycaemic control...

Introduction: Diabetes mellitus (DM) is a chronic disease that requires continuous medical care. Health care providers should adopt approaches that improve patient outcomes and adherence.Aims: To evaluate the adherence to Endocrinology ambulatory follow-up after elective hospital admission for decompensated DM and to determine the relationship between adherence and therapeutic success after discharge.Methods: Retrospective study of...

Background: Thyroid hormones modulate the lipoprotein and glucose metabolisms. In hyperthyroidism, insulin resistance is a frequent finding.Aim: To assess interrelationships between thyroid function, autoimmunity, lipid profile, glucose metabolism and other cardiovascular risk factors in patients with Graves’ disease.Methods: We recorded free T3 (FT3), free T4 (FT4), TSH, TSH receptor antibodies (TRAB), parameters of the lipid...

Introduction: Familial partial lipodystrophy (FPL) is an autosomal dominant disease characterized by selective loss of subcutaneous fat from the extremities and gluteal region, with lipohypertrophy of the face, neck and trunk. It is usually tightly linked with severe metabolic complications. FPL type 3 results from peroxisome proliferator-activated receptor gamma (PPARG) mutations.Case presentations: Fifty three-year-old woman, referred to endocrinology ...

Introduction: In patients with autoimmune thyroiditis, thyroid function appears to be related to increased cardiovascular risk. It was our objective to evaluate the relationship between TSH, insulin resistance, lipid profile, C-reactive protein (CRP) and homocysteine in patients with autoimmune thyroiditis (AIT).Methods: We analyzed the lipid profile, the CRP, anti-thyroid antibodies, homocysteine, folic acid, vitamin B12 levels and the insulin resistanc...

Introduction: Diabetic gastroparesis (DGP) is defined by delayed gastric emptying in the absence of mechanical obstruction caused by autonomic neuropathy. Only 5% of type 1 and 1% of type 2 diabetic patients combine the delay of gastric emptying with typical gastroparesis symptoms. This entity is usually identified in patients with least 10 years of diabetes evolution and is presented typically in the 4th to 5th decades of life in type 1 diabetes mellitus (T1DM). It is associa...

Introduction: Type 1 diabetes (T1D) is an important endocrine disease in the pediatric age group. The shift from pediatrics to adult health care providers is a critical period for adolescents with diabetes.Objective: Characterization of a pediatric population with T1D moved to adult health care between January/2001–April/2015.Methods: Cross-sectional study with retrospective analysis of medical records.R...

Introduction: Pituitary macroincidentalomas are rare, being found in only 0.2%–0.3% of the patients that undergo imaging studies for an unrelated reason. The majority of them are non-functioning adenomas.Case Report: Woman, 77 years-old, with type 2 diabetes mellitus, hypertension and primary hypothyroidism. She was referred to Endocrinology due to a pituitary incidentaloma (18 mm of maximal diameter, with extension to the cavernous sinus and to the...

Introduction: Subclinical hypothyroidism appears to be related with an increased risk of cardiovascular disease. It was our objective to evaluate the relationship between autoimmune thyroiditis, subclinical hypothyroidism, and cardiovascular risk factors.Methods: We evaluated thyroid function tests, autoimmunity, total cholesterol, LDL-cholesterol, HDL-cholesterol, triglycerides, ApoA1, ApoB, Lp(a), homocysteine, high sensibility CPR, folic acid, vitamin...

Introduction: Bariatric surgery improves lipid profile. A still unanswered question is whether this improvement is merely weight dependent or also results from factors inherent to specificities of the bariatric procedure itself. We aimed to study lipid profile 1 year after bariatric surgery and compare its changes between the different procedures in patients matched for initial weight and for weight loss.Methods: We retrospectively analysed patients subm...